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This course offers a comprehensive introduction to the scientific principles and methodologies that underpin modern drug development. You will gain an understanding of how therapeutic compounds are discovered, developed, and evaluated before reaching clinical application. The curriculum begins with an overview of the drug discovery pipeline, including target identification, lead optimization, and the transition from preclinical to clinical testing. Emphasis is placed on drug design and molecular docking, with instruction on key techniques, including molecular docking and virtual screening. You will gain the ability to design your own molecules and screen them with software, allowing for a research project. The course also covers fundamental concepts in pharmacokinetics and pharmacodynamics, including how to assess a compound’s absorption, distribution, metabolism, excretion, and toxicity (ADMET). You will be introduced to widely used computational tools for evaluating drug-likeness and predicting compound behavior in biological systems. No prior background in computational chemistry or programming is required, although familiarity with basic molecular biology and chemistry will be helpful. The course is designed for aspiring biomedical researchers, pharmaceutical scientists, bioengineers, and life science students interested in understanding how drugs are produced and brought to market. Through a combination of conceptual instruction and practical examples, you will acquire a foundational knowledge of drug design that can be applied in academic research, biotechnology, or further study.
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